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The study team described the receptor as an “opioid scavenger” as a result of its ability to lure Obviously transpiring opioids ahead of they can interact with classical opioid receptors.Gene expression Evaluation revealed that ACKR3 is highly expressed in various brain locations equivalent to essential opioid activity facilities. Moreover, its

Inside a latest study, we documented the identification as well as the characterization of a brand new atypical opioid receptor with one of a kind detrimental regulatory Attributes towards opioid peptides.1 Our results confirmed that ACKR3/CXCR7, hitherto often known as an atypical scavenger receptor for chemokines CXCL12 and CXCL11, is usually a b